Volunteers needed for trial

Volunteers are needed for The PROTECT V Trial – Led by Addenbrookes Hospital 

This new exciting trial, led by Dr Rona Smith at Addenbrookes, looks at how patients who are at particularly high risk of Covid-19, might be protected using a variety of drugs. The trial will enrol patients with kidney disease or autoimmune diseases.

This trial is funded by the UK Government and others including KRUK and Addenbrookes Charitable Trust.  

The first drug to be tried out as a prophylactic (preventative) treatment is niclosamide.  This is currently used to treat tapeworm infections, but laboratory experiments with niclosamide have shown it to be effective against the SARS-Cov2 virus, maybe by stopping it multiplying & penetrating into cells. In this trial, the drug will be taken as a nasal spray – to maximise its effect in the nasal tissues, where the virus mainly replicates itself.  

Volunteers will be given either niclosamide or placebo in a “blind” trial.

Here is the list of the centres in PROTECT-V.  If YOU as a patient are keen to join, then YOU should approach your own clinician and ask if their site is active.